To open a game in Engpsh, you can say "Open the game" or "Start the game." You can also say "Launch the game" or "Run the game." If you want to be more specific, you can say "Open [name of game] on my [device]" or "Start [name of game] on my [device]." For example, you could say "Open Fortnite on my PC" or "Start Minecraft on my phone."